The Carlson research group seeks to address the public health emergency of antibiotic resistance. Traditional antibacterial drugs directly kill bacteria, which results in the rapid evolution of resistance. Our innovative approach is to instead block the ability of bacteria to sense and respond to their surroundings. We are working to dramatically expand the community's understanding of how bacteria interact with their environment and how this can be disrupted to weaken a pathogen’s ability to cause disease.
Our research is highly multidisciplinary - members gain expertise in probe and inhibitor design and synthesis, mass spectrometry, biochemistry, proteomics and metabolomics, molecular biology, and microbiology.
4/2026: Congratulations Carter on receipt of the Lawrence (Larry) Que Jr., PhD. Fund for Excellence in Graduate Education, which will fund him through this summer!
4/2026: Congratulations Patty on receipt of the 2026-27 UMN Doctoral Dissertation Fellowship (DDF)! Such great news!
4/2026: Congratulations to Caroline on being awarded an American Association for University Women (AAUW) Fellowship!!
4/2026: Congratulations to Jacob on being awarded an NIH Predoctoral Fellowship (F31)!!
4/2026: Congratulations to lab alum Hannah Lembke for her position as a Method Development Scientist at EuroFins!
3/2026: Congratulations to Erin on being selected as an American Association for the Advancement of Science (AAAS) Fellow!
Covalent Inhibitors for Bacterial Histidine Kinases
Rodriguez, P. D.;† Fihn, C. A.;† Goswami, M.; Carlson, E. E. Chem. Comm., 2026, 62, 5482-5486.
https://pubs.rsc.org/en/content/articlelanding/2026/cc/d5cc06657c
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Learn more about the efforts of our department and Professor Carlson in an eNews article and on the departmental website to promote a welcoming and safe environment to learn and perform research.
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