Publications
82. Penicillin-binding protein redundancy in Bacillus subtilis enables growth during alkaline shock
Mitchell, S. M., Kearns, D. B. and Carlson, E. E. bioRxiv, 2023, 533529v1. Appl. Environ. Microbiol., 2024, 90, e0054823.
81. Modern Materials Provoke Ancient Behavior: Bacterial Resistance to Metal Nanomaterials.
Mitchell, S. L.; Hudson-Smith, N.; Sharan, D.; Haynes, C. L.; Carlson, E. E. ES: Nano, 2024, 11, 483-493.
https://doi.org/10.1039/D3EN00420A
Included in an issue dedicated to the memory of Joel Pedersen.
80. Cationic Polymers Enable Internalization of Negatively Charged Chemical Probe into Bacteria
Lembke, H. K.,† Espinasse, A.,† Hanson, M. G., Grimme, C. J., Tan, Z., Reinke, T. M. and Carlson, E. E. bioRxiv, 2023, 533359v1; ACS Chem. Biol., 2023, 18, 2063–2072.
79. Targeting multidrug resistant Staphylococcus infections with bacterial histidine kinase inhibitors
Espinasse, A.,† Goswami, M.,† Yang, J., Vorasin, O., Ji, Y.* and Carlson, E. E.* Chem Sci, 2023, 14, 5028-5037.
78. Evaluation of Expanded 2-Aminobenzothiazole Library for Inhibition of Pseudomonas aeruginosa Virulence Phenotypes
Fihn, C. A., Lembke, H. K., Gaulin, J., Bouchard, P., Penningroth, M. R., Crone, K. K., Vogt, G. A., Gilbertsen, A. J., Ayotte, Y., Couthino de Oliveira, L., Serrano-Wu, M. H., Drouin, N., Hung, D. T., Hunter, R. C. and Carlson, E. E. bioRxiv, 2023, 05.02.539119. Under Revision at peer reviewed journal.
77. Activity-Based Probes in Pathogenic Bacteria: Investigating Drug Targets and Molecule Specificity
Lembke, H. K. and Carlson, E. E. Curr. Opin. Chem. Biol, 2023, 76, 102359.
https://doi.org/10.1016/j.cbpa.2023.102359
Included in volume entitled, "Chemical Microbiology" edited by Erin Carlson and Pamela Chang.
76. Complex metal oxide nanomaterials directly generate reactive oxygen species and induce its production in bacteria.
Sharan, D.; Wolfson, D.; Gavin, A. G.; Green, C.; Lembke, P.; Hamers, R. J.; Feng, Z. V.; Carlson, E. E. ES: Nano, 2023, 10, 1978-1992.
Selected for Journal Cover
75. Metabolomics Reveals a "Trimeric" γ-Actinorhodin from Streptomyces coelicolor M145
Marshall, A. P.; Carlson, E. E. ChemBioChem 2023, 24, e202200757.
74. β-Lactam Titration Assays to Evaluate Penicillin-Binding Protein Selectivity
Sharan, D. and Carlson, E. E. Methods Mol. Biol. Under Review
73. Combined Structural Analysis and Molecular Dynamics Reveal Novel Penicillin-Binding Protein Inhibition Mode with β-Lactones
Flanders, P. L.; Contreras-Martel, C.; Brown, N. W.;† Shirley, J. D.;† Martins, A.; Nauta, K. M.; Dessen, A.; Carlson, E. E.;* Ambrose. E. A.* ACS Chem. Biol. 2022, 17, 3110-3120.
Selected for Journal Cover
72. Live-cell Profiling of Penicillin-Binding Protein Inhibitors in Escherichia coli MG1655
Shirley, J. D.; Nauta, K.; Carlson, E. E. ACS Infect. Dis. 2022, 8, 1241-1252.
71. Development of a single culture E. coli expression system for the enzymatic synthesis of fluorinated tyrosine and its incorporation into proteins
Olson, N. M.; Johnson, J. A.; Peterson, K. E.; Henisch, S. C.; Marshall, A. P.; Smanski, M. J.; Carlson, E. E.; Pomerantz, W. C. K. J. Fluor. Chem. 2022, 261-262, 110014.
70. Activity-Based ATP Analogue Probes for Bacterial Histidine Kinases
Lembke. H.K. and Carlson, E.E. Methods Enzym, 2022, 664, 59-84.
Included in volume entitled, "Chemical Microbiology" edited by Erin Carlson.
69. Expanded Profiling of β-Lactam Selectivity for Penicillin-Binding Proteins in Streptococcus pneumoniae D39
Sharan, D. and Carlson, E. E. Biol. Chem. 2022, 403, 433-443.
Invited for issue entitled, "Chemical Biology in Drug Discovery."
68. High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications
Murtha, A. N.; Kazi, M. I.; Schargel, R. D.; Cross, T.; Fihn, C. A.; Cottoir, V.; Carlson, E. E.; Boll, J. M.; Dörr, T. PLoS Pathogens, 2022, 18, e1010307.
67. Looks can be deceiving: Bacterial enzymes work through unanticipated mechanism
Shirley, J. D. and Carlson, E. E. Proc. Natl. Acad. Sci. USA 2021, 118, e2114568118.
Invited Commentary for: Biochemical reconstitution defines new functions for membrane-bound glycosidases in assembly of the bacterial cell wall. Proc. Natl. Acad. Sci. USA 2021, 118, e2103740118.
66. Targeting a Highly-Conserved Domain in Bacterial Histidine Kinases to Generate Inhibitors with Broad Spectrum Activity
Fihn, C. A. and Carlson, E. E. Curr. Opin. Microbiol. 2021, 61, 107-114. Invited.
65. Organization of Peptidoglycan Synthesis in Nodes and Separate Rings at Different Stages of Cell Division of Streptococcus pneumoniae
Perez, A. J.; Boersma, M. J.; Bruce, K. E.; Lamanna, M. M.; Shaw, S. L.; Tsui, H. T.; Taguchi, A.; Carlson, E. E.; VanNieuwenhze, M. S.; Winkler, M. E. Mol. Microbiol. 2021, 115, 1152-1169.
64. Comparison of Bioorthogonal β-Lactone Activity-Based Probes for Selective Labeling of Penicillin-Binding Proteins
Brown, N. W.;† Shirley, J. D.;† Marshall, A. P.; Carlson, E. E. ChemBioChem, 2021, 22, 193-202.
Named Very Important Paper (VIP)
Invited for Journal Cover
Invited article in special issue entitled, “Chemical Proteomics and Metabolomics.”
63. Modified nucleoside triphosphates in bacterial research for in vitro and live-cell applications
Espinasse, A.; Lembke, H. K.; Cao, A. A.; Carlson, E. E. RSC Chem. Bio. 2020, 1, 333-351.
Included in the Small Molecules for Chemical Biology topical collection!
62. 2-Aminobenzothiazoles inhibit virulence gene expression and block polymyxin resistance in Salmonella enterica
Thielen, M. K.; Vaneerd, C. K.; Goswami, M.; Carlson, E. E.; May, J. ChemBioChem, 2020, 21, 3500-3503.
61. Advancing Chemical Microbiology
Kiessling, L. L. and Carlson, E. E. ACS Chem. Biol., 2020, 15, 1115-1118.
Editorial for the special issue entitled, "Chemical Microbiology". Erin was the guest editor for this amazing issue!
60. Harnessing β-Lactam Antibiotics for Illumination of the Activity of Penicillin-Binding Proteins in Bacillus subtilis
Sharifzadeh, S.; Dempwolff, F.; Kearns, D. B.; Carlson, E. E. ACS Chem. Biol. 2020, 15, 1242-1251. BioRxiv, 2019, doi.org/10.1101/2019.12.19.881714.
Invited paper in Special Issue entitled, "Chemical Microbiology"
59. Enzyme-Targeted Fluorescent Small Molecule Probes for Bacterial Imaging
Marshall, A. P.;† Shirley, J. D.;† Carlson, E. E. Curr. Opin. Chem. Biol. 2020, 57, 155-165. Invited.
58. Chemical Tools for Selectivity Activity Profiling of Bacterial Penicillin-Binding Proteins
Sharifzadeh, S.; Brown, N. W.;† Shirley, J. D.;† Bruce, K. E.; Winkler, M. E.; Carlson, E. E. Methods Enzym. 2020, 638, 27-55.
57. Mechanistic Studies of Bioorthogonal ATP Analogs for Assessment of Histidine Kinase Autophosphorylation
Espinasse, A.; Wen, X.; Goodpaster, J. D.; Carlson, E. E. ACS Chem. Biol. 2020, 15, 1252-1260.
Invited paper in Special Issue entitled, "Chemical Microbiology"
56. Ion Mobility Mass Spectrometry as an Efficient Tool for Identification of Streptorubin B in Streptomyces coelicolor M145
Marshall, D. P.; Johnson, A. R.; Vega, M. M.; Thompson, R. J.; Carlson, E. E. J. Nat. Prod. 2020, 83, 159-163.
55. Gender Performance Gaps Across Different Assessment Methods and the Underlying Mechanisms: The Case of Incoming Preparation and Test Anxiety
Salehi, S.; Cotner, S.; Azarin, S.; Carlson, E. E.; Driessen, M.; Ferry, V. E.; Harcombe, W.; McGaugh, S.; Wassenberg, D.; Yonas, A.; Ballen, C. J. Front. Educ. 2019, 4, 107.
54. Chronic Exposure to Complex Metal Oxide Nanoparticles Elicits Rapid Resistance in Shewanella oneidensis MR-1
Mitchell, S. L.; Hudson-Smith, N. V.; Cahill, M. S.; Reynolds, B. N.; Frand, S. D.; Green, C. M.; Wang, C.; Hang, M. N.; Tapia Hernandez, R.; Hamers, R. J.; Feng, Z. V.; Haynes, C. L.; Carlson, E. E. Chem. Sci. 2019, 10, 9768-9781.
**Press releases from NSF, AAAS, Chemistry World, UMN, and Star Tribune.
53. Preferential Binding of Cytochrome c to an Anionic Ligand-Coated Gold Nanoparticle: A Complementary Computational and Experimental Approach
Tollefson, E. J.;† Allen, C. R.;† Chong, G.; Zhang, X.; Rozanov, N. D.; Bautista, A.; Cerda, J. J.; Pedersen, J. A.; Murphy, C. J.; Carlson, E. E.;* Hernandez, R.* ACS Nano, 2019, 13, 6856-6866.
52. Structure Elucidation of Macrolide Antibiotics Using MSn Analysis and Deuterium Labelling
Johnson, A. R.; Carlson, E. E. J. Am. Soc. Mass Spectrom., 2019, 30, 1464-1480.
51. Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2
Gehrke, E. J.; Zhang, X., Pimentel-Elardo, S. M.; Johnson, A. R.; Rees, C. A.; Jones S. E.; Hindra; Gehrke, S. S.; Turvey S.; Boursalie, S.; Hill, J. E.; Carlson, E. E.; Nodwell, J. R.; Elliot M. A. Elife, 2019, 8, e47691.
50. Biological Impact of Lithium Intercalating Complex Metal Oxides to Model Bacterium Bacilis subtillus
Feng, Z. V.; Miller, B.; Linn, T. G.; Pho, T.; Hoang, K. N. L.; Hang, M. N.; Mitchell, S. L.; Tapia Hernandez, R.; Carlson, E. E.; Hamers, R. J. Bacillus subtilis. Environ. Sci.: Nano 2019, 6, 305-314.
49. Activity-Based Protein Profiling Methods to Study Bacteria: The Power of Small Molecule Electrophiles
Sharifzadeh, S.; Shirley, J. D.; Carlson, E. E. In: Curr. Top. Microbiol. and Immunol. Springer, Berlin, Heidelberg. Edited Cravatt, B. F.; Hsu, K-L.; Weerapana, E. 2019. Invited Book Chapter.
48. Streptomyces volatile compounds influence exploration and microbial community dynamics by altering iron availability
Jones, S. E.; Pham, C. A.; Zambri, M.; McKillip, J.; Carlson, E. E.; Elliot, M. A. mBio 2019, 10, e00171-19.
https://mbio.asm.org/content/10/2/e00171-19
Selected as Editor's Pick!
Highlighted in: Editor’s Choice in Science: Funk, M. A. Stinky molecules undermine competitors. Science 2019, 364, 142.
Malone J: F1000Prime Recommendation of [Jones SE et al., MBio 2019 10(2)]. In F1000Prime, 21 Mar 2019; https://facultyopinions.com/article/735257236.
47. Disarming the virulence arsenal of Pseudomonas aeruginosa by blocking two-component system signaling
Goswami, M.; Espinasse, A.; Carlson, E. E. Chem. Sci., 2018, 10, 7332-7337.
Selected as part of the 2018 Chemical Science HOT Article Collection https://pubs.rsc.org/en/journals/articlecollectionlanding?sercode=sc&the...
46. Tiny Things with Enormous Impact: Nanotechnology in the Fight Against Infectious Disease
Mitchell, S. L. and Carlson, E. E. ACS Infect. Dis. 2018, 12, 1432-1435. Invited View Point.
45. Real-Time Visualization of In Vitro Transcription of a Fluorescent RNA Aptamer: An Experiment for the Upper-Division Undergraduate or First-Year Graduate Laboratory
Heili, J. M.; Gomez-Garcia, J.; Gaut, N. J.; Cash, B. W.; Aufdembrink, L. M.; Heffron, B. A.; Shirley, J. S.; Carlson, E. E.; Admala, K. P.; Engelhart, A. E. J. Chem. Ed. 2018, 95, 1867–1871.
44. Exploration of the effects of γ-phosphate modified ATP analogs on histidine kinase autophosphorylation
Chase, O. M.; Espinasse, A.; Carlson, E. E. Exploration of the effects of γ-phosphate modified ATP analogs on histidine kinase autophosphorylation. Biochemistry 2018, 57, 4368–4373.
43. Screening Serine/Threonine and Tyrosine Kinase Inhibitors for Histidine Kinase Inhibition
Wilke, K. E.; Fihn, C. A.; Carlson, E. E. Screening Serine/Threonine and Tyrosine Kinase Inhibitors for Histidine Kinase Inhibition. Bioorg. Med. Chem. 2018, 26, 5322-5326.
42. Rational Design Of Selective Adenine-Based Scaffolds For Inactivation Of Bacterial Histidine Kinases
Goswami, M.; Wilke, K. E.; Carlson, E. E. Rational Design Of Selective Adenine-Based Scaffolds For Inactivation Of Bacterial Histidine Kinases. J. Med. Chem., 2017, 60, 8170-8182.
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Mentored Publications